Back to search

Article

The Role of Clinical Pharmacogenetics and Opioid Interactions in Optimizing Treatment in Clinical Practice

2025-11-14

Abstract excerpt

<h4>Introduction: </h4> Opioids are the most commonly used analgesic drugs for acute and chronic severe pain metabolized in the liver via cytochrome P450 (CYP) and UDP-glucuronosyltransferase (UGT). <h4>Methods:</h4> A narrative review of the literature was conducted by searching MEDLINE and PubMed databases up to October 2025, using the English language as the only restriction. Relevant studies were identified us...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
a38275f2-9af4-5d22-b0c0-ecdb3d4ed6e1
DOI
10.20944/preprints202511.1078.v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
The Role of Clinical Pharmacogenetics and Opioid Interactions in Optimizing Treatment in Clinical PracticeDOI 10.20944/preprints202511.1078.v1
CYP2D6 phenotypes and opioid metabolism: the path to personalized analgesia.Semantic proximity
Pain management in the 21st century: utilization of pharmacogenomics and therapeutic drug monitoring.Semantic proximity
Pharmacogenetics of analgesics: toward the individualization of prescription.Semantic proximity
The value of CYP2D6 and OPRM1 pharmacogenetic testing for opioid therapy.Semantic proximity
Review of Opioid Pharmacogenetics and Considerations for Pain ManagementSemantic proximity
The potential of CYP2D6 phenotyping to improve opioid dosing strategiesSemantic proximity
A systematic review of pharmacogenetic guided opioid therapy for pain.Semantic proximity
Pain polymorphisms and opioids: An evidence based reviewSemantic proximity
Role of pharmacogenetics in variable response to drugs: focus on opioidsSemantic proximity
Reviewing pharmacogenetics to advance precision medicine for opioidsSemantic proximity
Clinical Pharmacogenetics Implementation Consortium (CPIC) guidelines for codeine therapy in the context of cytochrome P450 2D6 (CYP2D6) genotype.Semantic proximity
Improving Pain Management with Pharmacogenomics: A General Introduction.Semantic proximity
Select a neighboring publication to make it the new centre.