Article
Epigenetic abnormalities of classical Hodgkin lymphoma and its effect on immune escape.
Cell biochemistry and function - 1 Apr 2020
Liu Yizhen, Huang Renhong, Liu Lianfang, Meng Yanchun, Liu Xiaojian
Abstract excerpt
Classical Hodgkin lymphoma (cHL) is a particular kind of malignant tumour that originates from the B cells. The malignant phenotype of cHL is, at least in part, maintained by epigenetic aberrations, which primarily consist of abnormal histone methylation and acetylation. Progress has been made in clinical trials concerning the histone deacetylases inhibitors (HDACis) in cHL. Also, some demethylation regimens...
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