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Article

Improving the catalytic performance of Proteinase K from Parengyodontium album for use in feather degradation.

International journal of biological macromolecules - 1 Jul 2020

Ren Yaxin, Luo Huiying, Huang Huoqing, Hakulinen Nina, Wang Yaru, Wang Yuan, Su Xiaoyun, Bai Yingguo, Zhang Jie, Yao Bin, Wang Guozeng, Tu Tao

Abstract excerpt

Proteinase K (PROK) from Parengyodontium album hydrolyzes keratin, a major protein component of poultry feathers, which are an inexpensive and renewable protein resource. Based on structural studies for analysis of amino acid flexibility near the catalytic center, identification of highly conserved residues, and experimental screening, we obtained a mutant R218S with residual activity 1.6-fold higher than that of...

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Identifiers

PMID: 31706815
DOI: 10.1016/j.ijbiomac.2019.11.043

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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