Article
Optimal sequencing depth design for whole genome re-sequencing in pigs.
BMC bioinformatics - 8 Nov 2019
Jiang Yifan, Jiang Yao, Wang Sheng, Zhang Qin, Ding Xiangdong
Abstract excerpt
BACKGROUND: As whole-genome sequencing is becoming a routine technique, it is important to identify a cost-effective depth of sequencing for such studies. However, the relationship between sequencing depth and biological results from the aspects of whole-genome coverage, variant discovery power and the quality of variants is unclear, especially in pigs. We sequenced the genomes of three Yorkshire boars at an...
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