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Article

Application of massive parallel sequencing to whole genome SNP discovery in the porcine genome.

BMC genomics - 12 Aug 2009

Amaral Andreia J, Megens Hendrik-Jan, Kerstens Hindrik H D, Heuven Henri C M, Dibbits Bert, Crooijmans Richard P M A, den Dunnen Johan T, Groenen Martien A M

Abstract excerpt

BACKGROUND: Although the Illumina 1 G Genome Analyzer generates billions of base pairs of sequence data, challenges arise in sequence selection due to the varying sequence quality. Therefore, in the framework of the International Porcine SNP Chip Consortium, this pilot study aimed to evaluate the impact of the quality level of the sequenced bases on mapping quality and identification of true SNPs on a large...

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PMID: 19674453
DOI: 10.1186/1471-2164-10-374
PMCID: PMC2739861

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