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Mycobacterium abscessus virulence traits unraveled by transcriptomic profiling in amoeba and macrophages

8 Nov 2019

Abstract excerpt

Free-living amoebae are thought to represent an environmental niche in which amoeba-resistant bacteria may evolve towards pathogenicity. To get more insights into factors playing a role for adaptation to intracellular life, we characterized the transcriptomic activities of the emerging pathogen Mycobacterium abscessus in amoeba and murine macrophages (Mϕ) and compared them with the intra-amoebal transcriptome of...

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PMID: 31703112
DOI: 10.1371/journal.ppat.1008069

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