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Article

Morphological MRI phenotypes of multiple sclerosis differ in resting-state brain function.

Scientific reports - 7 Nov 2019

Pinter Daniela, Beckmann Christian F, Fazekas Franz, Khalil Michael, Pichler Alexander, Gattringer Thomas, Ropele Stefan, Fuchs Siegrid, Enzinger Christian

Abstract excerpt

We aimed to assess differences in resting-state functional connectivity (FC) between distinct morphological MRI-phenotypes in multiple sclerosis (MS). Out of 180 MS patients, we identified those with high T2-hyperintense lesion load (T2-LL) and high normalized brain volume (NBV; a predominately white matter damage group, WMD; N = 37) and patients with low T2-LL and low NBV (N = 37; a predominately grey matter...

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Identifiers

PMID: 31700126
DOI: 10.1038/s41598-019-52757-7
PMCID: PMC6838050

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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