Article
Secondary progressive and relapsing remitting multiple sclerosis leads to motor-related decreased anatomical connectivity.
PloS one - 1 Jan 2014
Lyksborg Mark, Siebner Hartwig R, Sørensen Per S, Blinkenberg Morten, Parker Geoff J M, Dogonowski Anne-Marie, Garde Ellen, Larsen Rasmus, Dyrby Tim B
Abstract excerpt
Multiple sclerosis (MS) damages central white matter pathways which has considerable impact on disease-related disability. To identify disease-related alterations in anatomical connectivity, 34 patients (19 with relapsing remitting MS (RR-MS), 15 with secondary progressive MS (SP-MS) and 20 healthy subjects underwent diffusion magnetic resonance imaging (dMRI) of the brain. Based on the dMRI, anatomical...
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