Article
Genomic characterisation of pulmonary subsolid nodules: mutational landscape and radiological features.
The European respiratory journal - 1 Feb 2020
Li Yanmeng, Li Xiao, Li Hao, Zhao Yifan, Liu Ziyang, Sun Kunkun, Zhu Xiang, Qi Qingyi, An Bei, Shen Danhua, Li Ruoyan, Liu Taorui, Mi Jiahui, Wang Lientu, Yang Fan, Bai Fan, Wang Jun
Abstract excerpt
BACKGROUND: Lung adenocarcinomas (LUADs) that display radiologically as subsolid nodules (SSNs) exhibit more indolent biological behaviour than solid LUADs. SSNs, commonly encompassing pre-invasive and invasive yet early-stage adenocarcinomas, can be categorised as pure ground-glass nodules and part-solid nodules. The genomic characteristics of SSNs remain poorly understood. METHODS: We subjected 154 SSN samples...
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