Article
MYD88 in the driver's seat of B-cell lymphomagenesis: from molecular mechanisms to clinical implications.
Haematologica - 1 Dec 2019
de Groen Ruben A L, Schrader Anne M R, Kersten Marie José, Pals Steven T, Vermaat Joost S P
Abstract excerpt
More than 50 subtypes of B-cell non-Hodgkin lymphoma (B-NHL) are recognized in the most recent World Health Organization classification of 2016. The current treatment paradigm, however, is largely based on 'one-size-fits-all' immune-chemotherapy. Unfortunately, this therapeutic strategy is inadequate for a significant number of patients. As such, there is an indisputable need for novel, preferably targeted,...
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