Article
MYD88 expression and L265P mutation in mature B-cell non-Hodgkin lymphomas.
Genetic testing and molecular biomarkers - 1 Jul 2015
Caner Vildan, Sen Turk Nilay, Baris Ikbal Cansu, Cetin Gokhan Ozan, Tepeli Emre, Hacioglu Sibel, Sari Ismail, Zencir Sevil, Dogu Mehmet Hilmi, Bagci Gulseren, Keskin Ali
Abstract excerpt
BACKGROUND: Myeloid differentiation primary response 88 (MYD88) is a common adaptor protein that is responsible for signaling from several receptors; mutations in this gene may play a role in the pathogenesis of lymphoma. AIM: We aimed to determine the MYD88 L265P mutation frequency, the level of MYD88 expression, and their associations with clinicopathological parameters in mature B-cell non-Hodgkin lymphomas...
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