Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Insertional mutagenesis in the zoonotic pathogen Chlamydia caviae.

PloS one - 1 Jan 2019

Filcek Kimberly, Vielfort Katarina, Muraleedharan Samada, Henriksson Johan, Valdivia Raphael H, Bavoil Patrik M, Sixt Barbara S

Abstract excerpt

The ability to introduce targeted genetic modifications in microbial genomes has revolutionized our ability to study the role and mode of action of individual bacterial virulence factors. Although the fastidious lifestyle of obligate intracellular bacterial pathogens poses a technical challenge to such manipulations, the last decade has produced significant advances in our ability to conduct molecular genetic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chick Embryo
Share to Chlamydia
Share to Chlamydia Infections

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chlamydia trachomatis

Share to Chlorocebus aethiops

Share to Mutagenesis, Insertional

Share to Vero Cells

Share to Zoonoses

Source

Open in PubMed Open full text

Identifiers

PMID: 31697687
DOI: 10.1371/journal.pone.0224324
PMCID: PMC6837515

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Insertional mutagenesis in the zoonotic pathogen Chlamydia caviae.PMID 31697687Read ↗

Site-specific, insertional inactivation of incA in Chlamydia trachomatis using a group II intron.Semantic proximity Read ↗

Molecular Genetic Analysis of Chlamydia SpeciesSemantic proximity Read ↗

A chemical mutagenesis approach to identify virulence determinants in the obligate intracellular pathogen Chlamydia trachomatis.Semantic proximity Read ↗

A platform supporting generation and isolation of random transposon mutants in Chlamydia trachomatisSemantic proximity Read ↗

Emancipating Chlamydia: Advances in the Genetic Manipulation of a Recalcitrant Intracellular PathogenSemantic proximity Read ↗

A renewed tool kit to explore Chlamydia pathogenesis: from molecular genetics to new infection modelsSemantic proximity Read ↗

Integrating chemical mutagenesis and whole-genome sequencing as a platform for forward and reverse genetic analysis of Chlamydia.Semantic proximity Read ↗

Frameshift mutations in a single novel virulence factor alter the in vivo pathogenicity of Chlamydia trachomatis for the female murine genital tract.Semantic proximity Read ↗

Homologues of the Chlamydia trachomatis and Chlamydia muridarum Inclusion Membrane Protein IncS Are Interchangeable for Early Development but Not for Inclusion Stability in the Late Developmental CycleSemantic proximity Read ↗

Isolation and characterization of a Chlamydia muridarum tc0237 mutant from a genetic screen that is attenuated in epithelial cells.Semantic proximity Read ↗

Chlamydia trachomatis ChxR is a transcriptional regulator of virulence factors that function in in vivo host-pathogen interactions.Semantic proximity Read ↗

The inclusion membrane protein IncS is critical for initiation of the Chlamydia intracellular developmental cycleSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.