Article
Chlamydia trachomatis ChxR is a transcriptional regulator of virulence factors that function in in vivo host-pathogen interactions.
Pathogens and disease - 1 Apr 2017
Yang Chunfu, Kari Laszlo, Sturdevant Gail L, Song Lihua, Patton Michael John, Couch Claire E, Ilgenfritz Jillian M, Southern Timothy R, Whitmire William M, Briones Michael, Bonner Christine, Grant Chris, Hu Pinzhao, McClarty Grant, Caldwell Harlan D
Abstract excerpt
Chlamydia trachomatis is an obligate intracellular pathogen characterized by a unique biphasic developmental cycle that alternates between infectious and non-infectious organisms. Chlamydial ChxR is a transcriptional activator that has been implicated in the regulation of the development cycle. We used a reverse genetics approach to generate three chxR null mutants. All three mutants grew normally in cultured...
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