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Article

A DNA Switch for Detecting Single Nucleotide Polymorphism within a Long DNA Sequence Under Denaturing Conditions.

Chemistry (Weinheim an der Bergstrasse, Germany) - 13 Jan 2020

Zhang Wenqing, Li Jiuxing, Salena Bruno, Li Yingfu

Abstract excerpt

Invited for the cover of this issue is the group of Yingfu Li at McMaster University. The image depicts a molecular switch for ultra-specific detection of DNA utilizing a guanine-quadruplex (up-right structure) resistant to denaturation by urea (ball-and-stick structures). Read the full text of the article at 10.1002/chem.201903536.

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PMID: 31696988
DOI: 10.1002/chem.201904777

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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