Small-bowel carcinomas associated with celiac disease: transcriptomic profiling shows predominance of microsatellite instability-immune and mesenchymal subtypes.

doi:10.1007/s00428-019-02675-w

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Article

Small-bowel carcinomas associated with celiac disease: transcriptomic profiling shows predominance of microsatellite instability-immune and mesenchymal subtypes.

Virchows Archiv : an international journal of pathology - 1 May 2020

Rizzo Francesca, Vanoli Alessandro, Sahnane Nora, Cerutti Roberta, Trapani Davide, Rinaldi Antonio, Sellitto Assunta, Ciacci Carolina, Volta Umberto, Villanacci Vincenzo, Calabrò Antonio, Arpa Giovanni, Luinetti Ombretta, Paulli Marco, Solcia Enrico, Di Sabatino Antonio, Sessa Fausto, Weisz Alessandro, Furlan Daniela

Abstract excerpt

Celiac disease (CD) is a risk factor for developing small-bowel carcinoma with a 14-fold higher risk compared with general population. As small-bowel carcinomas associated with CD (CD-SBCs) are extremely rare, very few molecular data are available about their pathogenesis, and information about their transcriptomic profiling is lacking. We generated RNA-seq data on 13 CD-SBCs, taken from the largest...

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PMID: 31696360
DOI: 10.1007/s00428-019-02675-w

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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