Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Unraveling the complex genetics of neural tube defects: From biological models to human genomics and back.

Genesis (New York, N.Y. : 2000) - 1 Nov 2021

Wolujewicz Paul, Steele John W, Kaltschmidt Julia A, Finnell Richard H, Ross Margaret Elizabeth

Abstract excerpt

Neural tube defects (NTDs) are a classic example of preventable birth defects for which there is a proven-effective intervention, folic acid (FA); however, further methods of prevention remain unrealized. In the decades following implementation of FA nutritional fortification programs throughout at least 87 nations, it has become apparent that not all NTDs can be prevented by FA. In the United States, FA...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Disease Models, Animal
Share to Folate and B Vitamins Research

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genetic Predisposition to Disease

Share to Genetic Syndromes and Imprinting

Share to Genomics

Share to Mutation

Share to Neural Tube Defects

Share to Prenatal Screening and Diagnostics

Source

Open in PubMed Open full text

Identifiers

PMID: 34713546
DOI: 10.1002/dvg.23459
PMCID: PMC8851409

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Unraveling the complex genetics of neural tube defects: From biological models to human genomics and back.PMID 34713546Read ↗

Investigations into the etiology of neural tube defectsSemantic proximity Read ↗

Finding the genetic mechanisms of folate deficiency and neural tube defects—Leaving no stone unturnedSemantic proximity Read ↗

Overview of Neural Tube Defects: Gene–Environment Interactions, Preventative Approaches and Future PerspectivesSemantic proximity Read ↗

Epidemiology of neural tube defectsSemantic proximity Read ↗

The continuing challenge of understanding, preventing, and treating neural tube defects.Semantic proximity Read ↗

The search for genetic determinants of human neural tube defects.Semantic proximity Read ↗

Genetic epidemiology of neural tube defects.Semantic proximity Read ↗

Micronutrient imbalance and common phenotypes in neural tube defectsSemantic proximity Read ↗

A quest for genetic causes underlying signaling pathways associated with neural tube defectsSemantic proximity Read ↗

Etiology and pathogenesis of human neural tube defectsSemantic proximity Read ↗

Syndromes, disorders and maternal risk factors associated with neural tube defects (IV).Semantic proximity Read ↗

Epidemiologic and genetic aspects of spina bifida and other neural tube defects.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.