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Article

A non-coding genetic variant associated with abdominal aortic aneurysm alters ERG gene regulation.

Human molecular genetics - 13 Mar 2020

Marsman Judith, Gimenez Gregory, Day Robert C, Horsfield Julia A, Jones Gregory T

Abstract excerpt

Abdominal aortic aneurysm (AAA) is a major cause of sudden death in the elderly. While AAA has some overlapping genetic and environmental risk factors with atherosclerosis, there are substantial differences, and AAA-specific medication is lacking. A recent meta-analysis of genome-wide association studies has identified four novel single-nucleotide polymorphisms (SNPs) specifically associated with AAA. Here, we...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 31691800
DOI: 10.1093/hmg/ddz256
PMCID: PMC7068029

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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