Genetic and Epigenetic Regulation of Aortic Aneurysms.

Abstract excerpt

Aneurysms are characterized by structural deterioration of the vascular wall leading to progressive dilatation and, potentially, rupture of the aorta. While aortic aneurysms often remain clinically silent, the morbidity and mortality associated with aneurysm expansion and rupture are considerable. Over 13,000 deaths annually in the United States are attributable to aortic aneurysm rupture with less than 1 in 3...

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• Aorta, Thoracic
• Aortic Aneurysm, Abdominal
• Aortic Aneurysm, Thoracic
• Extracellular Matrix
• Lipids
• Marfan Syndrome