Article
Partner Choice in Spontaneous Mitotic Recombination in Wild Type and Homologous Recombination Mutants of Candida albicans.
G3 (Bethesda, Md.) - 5 Nov 2019
Bellido Alberto, Ciudad Toni, Hermosa Belén, Andaluz Encarnación, Forche Anja, Larriba Germán
Abstract excerpt
Candida albicans, the most common fungal pathogen, is a diploid with a genome that is rich in repeats and has high levels of heterozygosity. To study the role of different recombination pathways on direct-repeat recombination, we replaced either allele of the RAD52 gene (Chr6) with the URA-blaster cassette (hisG-URA3-hisG), measured rates of URA3 loss as resistance to 5-fluoroorotic acid (5FOAR) and used CHEF...
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