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Article

Evidence for causal effects of lifetime smoking on risk for depression and schizophrenia: a Mendelian randomisation study

5 Nov 2019

Abstract excerpt

BACKGROUND: Smoking prevalence is higher amongst individuals with schizophrenia and depression compared with the general population. Mendelian randomisation (MR) can examine whether this association is causal using genetic variants identified in genome-wide association studies (GWAS). METHODS: We conducted two-sample MR to explore the bi-directional effects of smoking on schizophrenia and depression. For smoking...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 31689377
DOI: 10.1017/s0033291719002678

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