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Article

Using polygenic risk scores to investigate the evolution of smoking and mental health outcomes in UK biobank participants.

Acta psychiatrica Scandinavica - 1 Nov 2023

Balbuena Lloyd, Peters Evyn, Speed Doug

Abstract excerpt

OBJECTIVE: Mendelian randomization studies report a bi-directional relation between cigarette smoking and mental disorders, yet from a clinical standpoint, mental disorders are the focus of treatment. Here, we used an event history framework to understand their evolution in the life course. Our objective was to estimate the relative contribution of genetic predispositions and self-reported smoking status (never,...

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PMID: 37607129
DOI: 10.1111/acps.13601

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