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Article

Assessing causality in associations between cannabis use and schizophrenia risk: a two-sample Mendelian randomization study.

Psychological medicine - 1 Apr 2017

Gage S H, Jones H J, Burgess S, Bowden J, Davey Smith G, Zammit S, Munafò M R

Abstract excerpt

BACKGROUND: Observational associations between cannabis and schizophrenia are well documented, but ascertaining causation is more challenging. We used Mendelian randomization (MR), utilizing publicly available data as a method for ascertaining causation from observational data. METHOD: We performed bi-directional two-sample MR using summary-level genome-wide data from the International Cannabis Consortium (ICC)...

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Identifiers

PMID: 27928975
DOI: 10.1017/S0033291716003172
PMCID: PMC5341491

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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