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Recent advances in the CRISPR genome editing tool set

1 Nov 2019

Abstract excerpt

Genome editing took a dramatic turn with the development of the clustered regularly interspaced short palindromic repeats (CRISPR)-CRISPR-associated proteins (Cas) system. The CRISPR-Cas system is functionally divided into classes 1 and 2 according to the composition of the effector genes. Class 2 consists of a single effector nuclease, and routine practice of genome editing has been achieved by the development...

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PMID: 31685795
DOI: 10.1038/s12276-019-0339-7

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