Development and Application of CRISPR-Cas Based Tools

doi:10.3389/fcell.2022.834646

Article

Development and Application of CRISPR-Cas Based Tools

4 Apr 2022

Abstract excerpt

Abundant CRISPR-Cas systems in nature provide us with unlimited valuable resources to develop a variety of versatile tools, which are powerful weapons in biological discovery and disease treatment. Here, we systematically review the development of CRISPR-Cas based tools from DNA nuclease to RNA nuclease, from nuclease dependent-tools to nucleic acid recognition dependent-tools. Also, considering the limitations...

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