Article
Galleria mellonella as an Infection Model for Bacillus anthracis Sterne.
Frontiers in cellular and infection microbiology - 1 Jan 2019
Malmquist Jacob A, Rogan Madison R, McGillivray Shauna M
Abstract excerpt
Understanding bacterial virulence provides insight into the molecular basis behind infection and could identify new drug targets. However, assessing potential virulence determinants relies on testing in an animal model. The mouse is a well-validated model but it is constrained by the ethical and logistical challenges of using vertebrate animals. Recently the larva of the greater wax moth Galleria mellonella has...
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