Article
Development and evaluation of the Galleria mellonella (greater wax moth) infection model to study Brucella host-pathogen interaction
7 Dec 2022
Abstract excerpt
Brucellosis is a zoonotic disease caused by Gram-negative bacteria of the genus Brucella. These pathogens cause long-lasting infections, a process in which Brucella modifications in the lipopolysaccharide (LPS) and envelope lipids reduce pathogen-associated molecular pattern (PAMP) recognition, thus hampering innate immunity activation. In vivo models are essential to investigate bacterial virulence, mice being...
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