Modeling Klebsiella pneumoniae Pathogenesis by Infection of the Wax Moth Galleria mellonella

Abstract excerpt

The implementation of infection models that approximate human disease is essential for understanding pathogenesis at the molecular level and for testing new therapies before they are entered into clinical stages. Insects are increasingly being used as surrogate hosts because they share, with mammals, essential aspects of the innate immune response to infections. We examined whether the larva of the wax moth...

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