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Galleria mellonella as an alternative model of Coxiella burnetii infection

28 Mar 2014

Abstract excerpt

Coxiella burnetii is a Gram-negative intracellular bacterium and is the causative agent of the zoonotic disease Q fever. Several rodent and non-human primate models of virulent phase I C. burnetii [Nine Mile (NM)I] have been developed, and have been used to determine the efficacy of antibiotics and vaccine candidates. However, there are several advantages to using insect models to study host-microbe interactions,...

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PMID: 24677067
DOI: 10.1099/mic.0.077230-0

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