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Article

Antiviral Adaptor MAVS Promotes Murine Lupus With a B Cell Autonomous Role.

Frontiers in immunology - 1 Jan 2019

Sun Wenxiang, Wang Hongsheng, Qi Chen-Feng, Wu Juan, Scott Bethany, Bolland Silvia

Abstract excerpt

Systemic lupus erythematosus (SLE) is an autoimmune disorder characterized by increased production of autoantibodies, which commonly target nuclear antigens, and concomitant deposition of immune complexes that cause inflammation in tissues. SLE is often associated with increased systemic expression of type I interferons, in some cases due to dysregulation in nucleic acid-sensing innate pathways. There is strong...

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Identifiers

PMID: 31681326
DOI: 10.3389/fimmu.2019.02452
PMCID: PMC6805724

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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