Article
Polyunsaturated fatty acids and risk of Alzheimer's disease: a Mendelian randomization study.
European journal of nutrition - 1 Jun 2020
Tomata Yasutake, Larsson Susanna C, Hägg Sara
Abstract excerpt
PURPOSE: Observational studies have suggested that polyunsaturated fatty acids (PUFAs) may decrease Alzheimer's disease (AD) risk. In the present study, we examined this hypothesis using a Mendelian randomization analysis. METHODS: We used summary statistics data for single-nucleotide polymorphisms associated with plasma levels of n-6 PUFAs (linoleic acid, arachidonic acid) and n-3 PUFAs (alpha-linolenic acid,...
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