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Article

Lys-Arg mutation improved the thermostability of Bacillus cereus neutral protease through increased residue interactions.

World journal of microbiology & biotechnology - 31 Oct 2019

Osire Tolbert, Yang Taowei, Xu Meijuan, Zhang Xian, Li Xu, Niyomukiza Samuel, Rao Zhiming

Abstract excerpt

Neutral proteases have broad application as additives in modern laundry detergents and therefore, thermostability is an integral parameter for effective production of protein crystals. To improve thermostability, the contribution of individual residues of Bacillus cereus neutral protease was examined by site-directed mutagenesis. The Lys11Arg and Lys211Arg mutants clearly possessed improved thermostabilities (Tm...

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PMID: 31673794
DOI: 10.1007/s11274-019-2751-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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