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Transcriptome analysis reveals microvascular endothelial cell-dependent pericyte differentiation

30 Oct 2019

Abstract excerpt

Microvascular homeostasis is strictly regulated, requiring close interaction between endothelial cells and pericytes. Here, we aimed to improve our understanding of how microvascular crosstalk affects pericytes. Human-derived pericytes, cultured in absence, or presence of human endothelial cells, were studied by RNA sequencing. Compared with mono-cultured pericytes, a total of 6704 genes were differentially...

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PMID: 31666598
DOI: 10.1038/s41598-019-51838-x

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