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Article

Copy number detection in discordant monozygotic twins of Congenital Diaphragmatic Hernia (CDH) and Esophageal Atresia (EA) cohorts.

European journal of human genetics : EJHG - 1 Mar 2012

Veenma Danielle, Brosens Erwin, de Jong Elisabeth, van de Ven Cees, Meeussen Connie, Cohen-Overbeek Titia, Boter Marjan, Eussen Hubertus, Douben Hannie, Tibboel Dick, de Klein Annelies

Abstract excerpt

The occurrence of phenotypic differences between monozygotic (MZ) twins is commonly attributed to environmental factors, assuming that MZ twins have a complete identical genetic make-up. Yet, recently several lines of evidence showed that both genetic and epigenetic factors could have a role in phenotypic discordance after all. A high occurrence of copy number variation (CNV) differences was observed within MZ...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 22071887
DOI: 10.1038/ejhg.2011.194
PMCID: PMC3283183

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