Role of casual contact in drug-resistant tuberculosis transmission: a molecular epidemiology study.

doi:10.1093/ajrccm/aamag140

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Article

Role of casual contact in drug-resistant tuberculosis transmission: a molecular epidemiology study.

American journal of respiratory and critical care medicine - 1 Jul 2026

Gandhi Neel R, Naidoo Kogieleum, Lutchminarain Keeren, Omar Shaheed V, Yoshii Hikari, Willis Fay, Boodhram Resha, Gwala Thabisile, Campbell Angela, Coe Megan M, Evans A Nichole, Tang Linrui, Chitwood Melanie H, Hlathi Senzo R, Mbatha Patience N, Joseph Lavania, Van Der Meulen Hermina, Mlisana Koleka, Jenness Samuel M, Lurie Mark N, Kreiswirth Barry N, Warren Joshua L, Nelson Kristin N, Auld Sara C, Brust James C M, Cohen Ted, Mathema Barun, Shah N Sarita

Abstract excerpt

RATIONALE: Transmission is the primary driver of tuberculosis (TB) and drug-resistant TB (DR-TB) in high-burden countries; however, where and between whom spread occurs is poorly understood. OBJECTIVES: We conducted universal whole genome sequencing (WGS) to evaluate the role of casual contact in Mycobacterium tuberculosis transmission. METHODS: We recruited persons diagnosed with second-line DR-TB (eg,...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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PMID: 42089682
DOI: 10.1093/ajrccm/aamag140
PMCID: PMC13318217

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