Article
Influence of Estrogen Receptor Alpha Polymorphism on Bone Mineral Density in Iranian Children.
Human heredity - 1 Jan 2019
Montazeri-Najafabady Nima, Dabbaghmanesh Mohammad Hossein, Mohammadian Amiri Rajeeh, Mirzai Zahra
Abstract excerpt
BACKGROUND: Bone mass acquisition in childhood is directly linked to adult bone mineral density (BMD) and fracture risk. BMD is a heritable trait, more than 70% of its variability among a population is affected by genetic factors. OBJECTIVES: In the present study, we wanted to investigate the association between estrogen receptor alpha (ESR1) polymorphisms, PvuII (rs2234693) and XbaI (rs9340799), and bone area,...
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