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Article

Long Noncoding RNAs: From Clinical Genetics to Therapeutic Targets?

Journal of the American College of Cardiology - 15 Mar 2016

Boon Reinier A, Jaé Nicolas, Holdt Lesca, Dimmeler Stefanie

Abstract excerpt

Recent studies suggest that the majority of the human genome is transcribed, but only about 2% accounts for protein-coding exons. Long noncoding RNAs (lncRNAs) constitute a heterogenic class of RNAs that includes, for example, intergenic lncRNAs, antisense transcripts, and enhancer RNAs. Moreover, alternative splicing can lead to the formation of circular RNAs. In support of putative functions, GWAS for...

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PMID: 26965544
DOI: 10.1016/j.jacc.2015.12.051

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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