Article
Variants in ANRIL gene correlated with its expression contribute to myocardial infarction risk.
Oncotarget - 21 Feb 2017
Cheng Jie, Cai Meng-Yun, Chen Yu-Ning, Li Zhi-Cheng, Tang Sai-Sai, Yang Xi-Li, Chen Can, Liu Xinguang, Xiong Xing-Dong
Abstract excerpt
ANRIL (antisense non-coding RNA in the INK4 locus), located at the 9p21.3 locus, has been known to be closely associated with the risk of coronary artery disease (CAD). To date, studies of the 9p21.3 variants on CAD risk mainly focus on the non-coding region of ANRIL. However, the biological significance of the variants on ANRIL promoter and exons is still unknown. Here we investigate whether the variants on...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
