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The lncRNA ANRIL regulates endothelial dysfunction by targeting the let‐7b/TGF‐βR1 signalling pathway

11 Aug 2020

Abstract excerpt

The long noncoding RNA antisense noncoding RNA in the INK4 locus (ANRIL) plays a critical role in the development of atherosclerosis. However, the precise effect of ANRIL on endothelial dysfunction remains unclear. In this study, we investigated ANRIL expression in patients with coronary artery disease and elucidated the molecular mechanism underlying its effect. ANRIL expression was detected in the blood plasma...

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PMID: 32783191
DOI: 10.1002/jcp.29993

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