Article
Human phenotypes associated with GATA-1 mutations.
Gene - 31 Dec 2008
Ciovacco Wendy A, Raskind Wendy H, Kacena Melissa A
Abstract excerpt
GATA-1 is one of the six members of the GATA gene family, a group of related transcription factors discovered in the 1980s. In the past few decades, the crucial role of GATA-1 in normal human hematopoiesis has been delineated. As would be expected, mutations in GATA-1 have subsequently been found to have important clinical significance, and are directly linked to deregulated formation of certain blood cell...
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