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The association between omega-3 and omega-6 polyunsaturated fatty acids and 3 cardiac inflammatory diseases: A Mendelian randomization study.

Medicine - 23 Jan 2026

Song Zhuoxuan, Li Letai, He Aiwei, Chen Tingting, Liu Rongjia, Gao Yuanxueying, Jiang Yingjiu, Leng Jiajie

Abstract excerpt

The Mediterranean diet exerts beneficial effects on cardiovascular health, though many of its underlying mechanisms remain undefined. While omega-3/6 polyunsaturated fatty acids (PUFAs) present in this dietary pattern may influence cardiac inflammatory conditions, their specific roles in heart diseases require further investigation. Independent single nucleotide polymorphisms associated with omega-3/6 PUFAs and 3...

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Fatty Acids, Omega-3
Fatty Acids, Omega-6
Genome-Wide Association Study
Inflammation
Mendelian Randomization Analysis

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Polymorphism, Single Nucleotide

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PMID: 41578468
DOI: 10.1097/MD.0000000000042278
PMCID: PMC12851787

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