Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The impact of gene-environment interaction and correlation on the interpretation of heritability.

Acta biotheoretica - 1 Sept 2012

Tal Omri

Abstract excerpt

The presence of gene-environment statistical interaction (GxE) and correlation (rGE) in biological development has led both practitioners and philosophers of science to question the legitimacy of heritability estimates. The paper offers a novel approach to assess the impact of GxE and rGE on the way genetic and environmental causation can be partitioned. A probabilistic framework is developed, based on a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Analysis of Variance
Share to Gene-Environment Interaction
Share to Linear Models

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Mathematical Concepts

Share to Models, Genetic

Share to Models, Statistical

Share to Phenotype

Source

Identifiers

PMID: 21863336
DOI: 10.1007/s10441-011-9139-8

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The impact of gene-environment interaction and correlation on the interpretation of heritability.PMID 21863336Read ↗

The Meaning of "Cause" in Genetics.Semantic proximity Read ↗

On the causal interpretation of heritability from a structural causal modeling perspective.Semantic proximity Read ↗

Probabilistic epigenesis.Semantic proximity Read ↗

Biometric and developmental gene-environment interactions: looking back, moving forward.Semantic proximity Read ↗

Bias and Precision of Parameter Estimates from Models Using Polygenic Scores to Estimate Environmental and Genetic Parental Influences.Semantic proximity Read ↗

Heritability.Semantic proximity Read ↗

The genotype-phenotype distinction: from Mendelian genetics to 21st century biology.Semantic proximity Read ↗

Developmental associations between traits: covariance and beyond.Semantic proximity Read ↗

Beyond genotype-phenotype maps: Toward a phenotype-centered perspective on evolution.Semantic proximity Read ↗

Assessing Orthogonality in Gene-Environment Interaction Studies Using Polygenic Indices.Semantic proximity Read ↗

Genetic Causation in Complex Regulatory Systems: An Integrative Dynamic Perspective.Semantic proximity Read ↗

Heritability in the genomics era--concepts and misconceptions.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.