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Article

Race-dependent association of sulfidogenic bacteria with colorectal cancer

2 Feb 2017

Abstract excerpt

OBJECTIVE: Colorectal cancer (CRC) incidence is higher in African Americans (AAs) compared with non-Hispanic whites (NHWs). A diet high in animal protein and fat is an environmental risk factor for CRC development. The intestinal microbiota is postulated to modulate the effects of diet in promoting or preventing CRC. Hydrogen sulfide, produced by autochthonous sulfidogenic bacteria, triggers proinflammatory...

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PMID: 28153960
DOI: 10.1136/gutjnl-2016-313321

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