Article
Wheat germ agglutinin-binding protein changes in highly malignant Friend leukemia cells metastasizing to the liver.
Clinical & experimental metastasis - 1 Jan 2000
Elia G, Ferrantini M, Belardelli F, Proietti E, Gresser I, Amici C, Benedetto A
Abstract excerpt
We have used binding of radioactive lectins (i.e. Concanavalin A (ConA), Wheat Germ Agglutinin (WGA) and Ricinus communis agglutinin I (RCAI)) to membrane glycoproteins separated in SDS gel electrophoresis, to detect specific carbohydrate changes in plasma membrane proteins of in vivo passaged Friend erythroleukemia cells (FLC). These cells are highly metastatic to the liver, whereas the original in vitro...
Topics
- Animals
- Carbohydrate Metabolism
- Cell Division
- Electrophoresis, Polyacrylamide Gel
- Female
- Friend murine leukemia virus
- Leukemia, Erythroblastic, Acute
- Liver Neoplasms
- Male
- Membrane Glycoproteins