Article
Modification of the erythrocyte surface in rats bearing Yoshida ascites sarcoma is brought about by a tumour variant of alpha2-macroglobulin.
The Biochemical journal - 1 Mar 1997
Sanjay A, Kalraiya R D, Mehta N G
Abstract excerpt
Erythrocytes from the circulation of rats bearing Yoshida ascites sarcoma exhibit higher concanavalin A (ConA)-mediated agglutinability than those from normal animals. A tetrameric glycoprotein of subunit molecular mass 170 kDa, purified from the cell-free ascites fluid, was found to confer highe...
Topics
- Agglutination
- Amino Sugars
- Animals
- Ascites
- Concanavalin A
- Dose-Response Relationship, Drug
- Embryo, Mammalian
- Erythrocyte Membrane
- Erythrocytes
- Genetic Variation
- Monosaccharides
- N-Acetylneuraminic Acid
- Peptide Mapping
- Protein Binding
- Rats
- Rats, Wistar
- Sarcoma, Yoshida
- Tissue Distribution