Article
An in silico Approach for Integrating Phenotypic and Target-based Approaches in Drug Discovery.
Molecular informatics - 1 Jan 2020
Iwata Hiroaki, Kojima Ryosuke, Okuno Yasushi
Abstract excerpt
Phenotypic and target-based approaches are useful methods in drug discovery. The phenotypic approach is an experimental approach for evaluating the phenotypic response. The target-based approach is a rational approach for screening drug candidates targeting a biomolecule that causes diseases. These approaches are widely used for drug discovery. However, two serious problems of target deconvolution and...
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