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Article

Maternal treatment with aripiprazole prevents the development of a valproic acid-induced autism-like phenotype in juvenile male mice.

Behavioural pharmacology - 1 Apr 2023

de Oliveira Ferreira Emerson, Pessoa Gomes Jéssica Maria, Neves Kelly Rose Tavares, Lima Francisco Arnaldo Viana, de Barros Viana Glauce Socorro, de Andrade Geanne Matos

Abstract excerpt

Autism spectrum disorder (ASD) describes a heterogeneous group of neurodevelopmental conditions characterized by deficits in social communication and repetitive behaviors. Aripiprazole (APZ) is an atypical antipsychotic that can safeguard mice against autism-like behavior induced by valproic acid (VPA). In the present study, we examined the effects of maternal treatment with APZ (10 mg/kg) in juvenile mice...

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PMID: 36853856
DOI: 10.1097/FBP.0000000000000718

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026.

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