Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Esophageal squamous cell carcinoma with EP300 mutations displays distinct genetic characteristics relevant to neoadjuvant chemoradiotherapy.

World journal of surgical oncology - 2 Jan 2025

Lai Yutian, Dong Yingxian, Tian Long, Li Hongjun, Ye Xinyi, Hu Yang

Abstract excerpt

BACKGROUND: EP300 mutation is common in esophageal squamous cell carcinoma (ESCC). We aimed to analyze the influence of EP300 mutation on treatment effect and prognosis in ESCC patients underwent neoadjuvant chemoradiotherapy. METHOD: Thirty ESCC patients treated with neoadjuvant chemoradiotherapy (nCRT) were enrolled in this study. After assessment of treatment response, transcriptome analyses and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Biomarkers, Tumor
Share to Chemoradiotherapy

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to E1A-Associated p300 Protein

Share to Esophageal Neoplasms

Share to Esophageal Squamous Cell Carcinoma

Share to Follow-Up Studies

Share to Neoadjuvant Therapy

Share to Survival Rate

Source

Open in PubMed Open full text

Identifiers

PMID: 39748249
DOI: 10.1186/s12957-024-03642-9
PMCID: PMC11694467

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Esophageal squamous cell carcinoma with EP300 mutations displays distinct genetic characteristics relevant to neoadjuvant chemoradiotherapy.PMID 39748249Read ↗

EP300-mutated esophageal squamous cell carcinoma exhibits unique genetic features：an Experimental StudySemantic proximity Read ↗

EP300 as an oncogene correlates with poor prognosis in esophageal squamous carcinomaSemantic proximity Read ↗

Identifying key mutations of radioresponsive genes in esophageal squamous cell carcinoma.Semantic proximity Read ↗

Multiomic Landscape of Esophageal Squamous Cell Carcinoma: Molecular Profiles and Predictors of Neoadjuvant Chemoradiotherapy Responsiveness and ResistanceSemantic proximity Read ↗

The integrated molecular and histological analysis defines subtypes of esophageal squamous cell carcinoma.Semantic proximity Read ↗

Molecular alterations and clinical relevance in esophageal squamous cell carcinoma.Semantic proximity Read ↗

A combined approach on the impact of EP300 overexpression on drug resistance, invasion and stemness in breast cancerSemantic proximity Read ↗

Stemness and NK-like signatures define a subtype of esophageal squamous cell carcinoma with poor prognosisSemantic proximity Read ↗

Molecular classification of esophageal squamous cell carcinoma based on immunogenic cell death related damage-associated molecular pattern gene signatureSemantic proximity Read ↗

A cancer-array approach elucidates the immune escape mechanism and defects in the DNA repair system in esophageal squamous cell carcinoma.Semantic proximity Read ↗

In silico analysis reveals EP300 as a panCancer inhibitor of anti-tumor immune response via metabolic modulation.Semantic proximity Read ↗

Comprehensive landscape of resistance mechanisms for neoadjuvant therapy in esophageal squamous cell carcinoma by single-cell transcriptomicsSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.