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Article

Salidroside Delays Cellular Senescence by Stimulating Mitochondrial Biogenesis Partly through a miR-22/SIRT-1 Pathway

12 Sept 2019

Abstract excerpt

Calorie restriction (CR) is a nongenetic intervention with a robust effect on delaying aging in mammals and other organisms. A mild stimulation on mitochondrial biogenesis induced by CR seems to be an important action mode for its benefits. Here, we reported that a component isolated from Rhodiola rosea L ., salidroside, delays replicative senescence in human fibroblasts, which is related to its stimulation on...

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PMID: 31612074
DOI: 10.1155/2019/5276096

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