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Article

The Effect of Resveratrol on Mitochondrial Function in Myoblasts of Patients with the Common m.3243A>G Mutation.

Biomolecules - 24 Jul 2020

Motlagh Scholle Leila, Schieffers Helena, Al-Robaiy Samiya, Thaele Annemarie, Dehghani Faramarz, Lehmann Urban Diana, Zierz Stephan

Abstract excerpt

Mitochondrial function is essential for ATP-supply, especially in response to different cellular stressors. Increased mitochondrial biogenesis resulting from caloric restriction (CR) has been reported. Resveratrol (RSV) is believed to mimic the physiological effects of CR mainly via a sirtuin (SIRT) 1-dependent pathway. The effect of RSV on the physiological function of mitochondrial respiratory complexes was...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 32722320
DOI: 10.3390/biom10081103
PMCID: PMC7464358

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