Article
During yeast chronological aging resveratrol supplementation results in a short-lived phenotype Sir2-dependent.
Redox biology - 1 Aug 2017
Orlandi Ivan, Stamerra Giulia, Strippoli Maurizio, Vai Marina
Abstract excerpt
Resveratrol (RSV) is a naturally occurring polyphenolic compound endowed with interesting biological properties/functions amongst which are its activity as an antioxidant and as Sirtuin activating compound towards SIRT1 in mammals. Sirtuins comprise a family of NAD+-dependent protein deacetylases that are involved in many physiological and pathological processes including aging and age-related diseases. These...
Topics
- Acetylation
- Gene Expression Regulation, Fungal
- Microbial Viability
- Phenotype
- Phosphoenolpyruvate Carboxykinase (GTP)
- Resveratrol
- Saccharomyces cerevisiae
- Silent Information Regulator Proteins, Saccharomyces cerevisiae
- Sirtuin 2
- Stilbenes